“If causally associated, the supplementation of vitamin D may help in preventing insulin resistance and subsequent T2DM”

This is the last line of the abstract of the paper you linked to.

This is the point I’m trying to make. There is a lot of vitatmin D research out there, but it is correlational. When you have a correlation causality could go either way, or both observations could be caused by another factor, or factors.

If you take a close look at the body of vitamin D research it is simply not strong enough to recommend supplementation.

Insulin receptors are also located throughout the body, but this doesn’t mean giving people lots of insulin is a good thing.

Drs aren’t prescribing vitamin D because of commercialism but because of a very poor interpretation of the literature.

I agree – “the science is as shaky as that for statins.” but this is because of blatant commercialism.

Vitamin D is not patentable and is less subject to commercial misinformation

http;//www.vitamindcouncil.org is an independent organization.

A pubmed search on Vitamin D found 59965 references.

an example is the following that can be downloaded in full.

Relationship between insulin resistance and plasma vitamin D in adults
http://www.dovepress.com/relationship-between-insulin-resistance-and-plasma-vitamin-d-in-adults-peer-reviewed-article-DMSO
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2014:7 297–303

Vitamin D is not just related to rickets; it is involved in some 500 metabolic processes and every cell in the body has vit d receptors. But it is far from a cure all.

Really?

Most of the vitamin D research I’ve seen is of a correlation between low levels of vitamin D and poor health. There is very little well conducted supplementation evidence that shows increasing vitamin D levels is good for anything. Could be that low vitamin D levels are a result of chronic disease (along with maybe, poorer muscle function, cancer, heart disease, diabetes, and all the other things vitamin D is supposed to prevent). It even seems to be a struggle to find good evidence that supplementing vitamin D improves bone density.

There may be all sorts of possible reasons for the relationship between low serum D and ill health. The evidence is not there that supports the sort of widespread prescription of supplements that is going on.

Take a look – the science is as shaky as that for statins.

http://www.marksdailyapple.com/forum/thread87791.html

““speed of walking over a 4-metre distance…”

Surely you mean kilometres!???”

Maybe at 71 and before the magnesium supplementation 4 metres was all they could manage 😉

John, at the bottom of your post, the reference to the article is a bit quaint, “random mice”? 😉

Surely you mean kilometres!???

In the US the average daily intake is below the RDI and I suspect the same is true for the UK as, after centuries of cultivation, soil and consequently plants are short of magnesium. In my own garden years ago we had raspberry canes (5 ft) and miserable. Threw a pound of epsom salts (MgSO4) on them – 8 ft tall. Take it or leave it!

On a more serious note, I know of a couple relatives that take a good amount of magnesium oxide (likely the oxide version) daily. I’ve been told that it is their favorite supplement, giving extra pep for the day.